A Phenolic Compound From Active Extract of Endophytic Fungus Isolated From Leaf Stalk of Jambu Bol (Syzygium malaccense)
Keywords:Syzygium malaccense, Daldinia eschsholtzii, antioxidant, antibacterial, phenolic compound
Syzygium malaccense plant or jambu bol has been known as a medicinal plant. Jambu bol (S. malaccense) as a herbal medicinal plant has been widely studied in various countries. However, finding sources of raw materials for new drugs remains a top priority in overcoming various problems, such as resistance and metabolic disorders caused by free radicals.This study aims to identify endophytic fungal species from the plant S. malaccense molecularly which has the potential as antibacterial and antioxidant to identify secondary metabolites it contains.The method used for antibacterial testing is the agar diffusion method with the concentration used being 400 ppm with a positive control ratio of tetracycline with a concentration of 30 ppm.Antioxidant testing using the DPPH method. The results were isolated of endophytic fungi from leaves that had potential as antibacterial and Antioxidants is identified as Daldinia eschsholtzii producing inhibition zones strong criteria with the highest percentage in YTD3 isolate 17.38±0.89 in E.coli, 17.28±0.1 (mm), at S. typhi, 17.77±2.73 (mm), in S. aureus and 17.45±0.54 (mm), in B. subtilis and IC50 value 33.83.The secondary metabolite compound produced was identified as 3-hydroxy-4-(hydroxy(4-hydroxyphenyl)methyl)dihydrofuran-2-one. Further research is needed, namely testing compounds that have been identified as sources of new drug raw materials.
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