Advanced Lung Nodule Staging through 3D-ResNet: Classifying CT Images for Enhanced Diagnostic Precision
Keywords:
3D Convolutional Neural Networks, CT Images, Lung Nodules, Lung Nodule Analysis, Lung Image Database ConsortiumAbstract
Lung nodules present a critical challenge in pulmonary diagnostics, necessitating accurate staging for optimal treatment planning. This study proposes an advanced approach employing 3DResNet for precise lung nodule staging via CT image classification. Leveraging the power of three-dimensional convolutional neural networks (3D CNNs), this methodology aims to enhance diagnostic precision by categorizing lung nodules into distinct stages based on radiological features extracted from CT images. The 3DResNet architecture enables robust feature learning by analyzing spatial relationships within volumetric data, facilitating the discrimination of subtle nodule characteristics indicative of different disease stages. The amalgamation of LIDC's (Lung Image Database Consortium) extensive annotated data and LUNA's (LUng Nodule Analysis) meticulously curated nodule annotations provides a robust foundation for training and validating the 3DResNet model. By capitalizing on this amalgamated dataset, the model endeavors to achieve heightened accuracy and generalization in classifying nodule stages, thus empowering clinicians with nuanced insights into disease progression. By training on a comprehensive dataset encompassing diverse nodule presentations and stages, the model endeavors to achieve superior accuracy in stage classification. The outcomes are expected to offer clinicians refined insights into disease progression, aiding in informed decision-making for personalized patient care and treatment strategies.
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Ardila, D., Kiraly, A. P., Bharadwaj, S., et al. (2019). End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nature Medicine, 25(6), 954-961.
Ciompi, F., Chung, K., Van Riel, S. J., et al. (2015). Towards automatic pulmonary nodule management in lung cancer screening with deep learning. Scientific Reports, 5, 1-10.
Han, H., Wang, H., Kamdar, M. R., & Nelson, D. B. (2017). Detection of individual metastatic cancer cells in human cerebrospinal fluid using a three-dimensional immunocapture and imaging method. PloS one, 12(4), e0175161.
Huang, P., Park, S., Yan, R., et al. (2019). Added Value of Computer-Aided CT Image Features for Early Lung Cancer Diagnosis with Small Pulmonary Nodules: A Matched Case-Control Study. Radiology, 293(2), 364-372.
Li, Q., Cao, L., Yang, G., et al. (2019). 3D deep learning from CT scans predicts tumor invasiveness of subcentimeter pulmonary adenocarcinomas. Cancer Research, 79(13), 1623-1633.
Liu, Y., Kim, J., Balagurunathan, Y., et al. (2017). Radiomic features are associated with EGFR mutation status in lung adenocarcinomas. Clinical Lung Cancer, 18(5), e435-e441.
Nishio, M., Sugiyama, O., Yakami, M., et al. (2018). Computer-aided diagnosis of lung nodule classification between benign nodule, primary lung cancer, and metastatic lung cancer at different image sizes using a deep convolutional neural network with transfer learning. PloS one, 13(10), e0200721.
Setio, A. A. A., Traverso, A., De Bel, T., et al. (2017). Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the LUNA16 challenge. Medical Image Analysis, 42, 1-13.
Shen, W., Zhou, M., Yang, F., et al. (2018). Multi-crop convolutional neural networks for lung nodule malignancy suspiciousness classification. Pattern Recognition, 76, 282-293.
Teramoto, A., Fujita, H., & Yamamuro, O. (2018). Automated detection of pulmonary nodules in PET/CT images: Ensemble false-positive reduction using a convolutional neural network technique. Medical Physics, 45(12), 5618-5626.
Wang, S., Shi, J., Ye, Z., et al. (2019). Predicting EGFR mutation status in lung adenocarcinoma on computed tomography image using deep learning. European Respiratory Journal, 53(3), 1800986.
Ardila, D., Kiraly, A. P., Bharadwaj, S., et al. (2019). End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography. Nature Medicine, 25(6), 954-961.
Ciompi, F., Chung, K., Van Riel, S. J., et al. (2015). Towards automatic pulmonary nodule management in lung cancer screening with deep learning. Scientific Reports, 5, 1-10.
Han, H., Wang, H., Kamdar, M. R., & Nelson, D. B. (2017). Detection of individual metastatic cancer cells in human cerebrospinal fluid using a three-dimensional immunocapture and imaging method. PloS one, 12(4), e0175161.
Huang, P., Park, S., Yan, R., et al. (2019). Added Value of Computer-Aided CT Image Features for Early Lung Cancer Diagnosis with Small Pulmonary Nodules: A Matched Case-Control Study. Radiology, 293(2), 364-372.
Li, Q., Cao, L., Yang, G., et al. (2019). 3D deep learning from CT scans predicts tumor invasiveness of subcentimeter pulmonary adenocarcinomas. Cancer Research, 79(13), 1623-1633.
Liu, Y., Kim, J., Balagurunathan, Y., et al. (2017). Radiomic features are associated with EGFR mutation status in lung adenocarcinomas. Clinical Lung Cancer, 18(5), e435-e441.
Nishio, M., Sugiyama, O., Yakami, M., et al. (2018). Computer-aided diagnosis of lung nodule classification between benign nodule, primary lung cancer, and metastatic lung cancer at different image size using deep convolutional neural network with transfer learning. PloS one, 13(10), e0200721.
Setio, A. A. A., Traverso, A., De Bel, T., et al. (2017). Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the LUNA16 challenge. Medical Image Analysis, 42, 1-13.
Shen, W., Zhou, M., Yang, F., et al. (2018). Multi-crop convolutional neural networks for lung nodule malignancy suspiciousness classification. Pattern Recognition, 76, 282
Tang, L., Zheng, X., Huang, S., et al. (2021). Lung Nodule Classification using 3D Deep Residual Convolutional Neural Network. BioMed Research International, 2021.
Wang, Y., Yang, X., Feng, W., et al. (2021). 3D-ResNet-Based Lung Nodule Classification Using CT Images. Journal of Healthcare Engineering, 2021.
Li, Y., Zhang, D., Zhang, Z., et al. (2021). A novel 3DResNet-based deep learning method for lung nodule classification in CT images. Computer Methods and Programs in Biomedicine, 210.
Zhang, Y., Yu, Y., Zhang, Y., et al. (2021). 3DResNet-based lung nodule classification using CT images: performance and interpretability. Journal of X-Ray Science and Technology, 29(6), 1119-1131.
Liu, Y., Wang, Y., Tang, L., et al. (2021). 3DResNet-Based Classification of Pulmonary Nodules in CT Images. IEEE Access, 9, 96461-96472.
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