Building Trust in Artificial Intelligence: An Explainable Deep Learning Framework for Brain Disease Detection

Authors

  • P. V. Siva Kumar, Gautham Mallipeddi, Srinivasa Deepesh Kommineni, Tapan Ganesh Naram, Akhilesh Kumandan Kottakota

Keywords:

Alzheimer’s disease, Brain Tumor, Convolutional Neural Network, Deep Learning, Explainable AI, Magnetic Resonance Image (MRI), Multiple Sclerosis, Transfer Learning

Abstract

Artificial Intelligence (AI) has shown promising results across various research fields. However, there is significant concern about its application in medicine due to the critical need for high accuracy and reliable data in this field. A major issue with many existing machine learning models is their lack of transparency; they do not explain the reasoning behind their outputs. This opacity leads to a lack of trust among healthcare professionals, who are hesitant to rely on such technology for critical decisions. Our research aims to address this concern by developing an Explainable Artificial Intelligence (XAI) model. This model not only classifies MRI images but also provides clear explanations for its predictions. By highlighting the specific regions of the brain that influenced each decision, our XAI model helps bridge the gap between AI and clinical practice. This approach empowers clinicians to identify brain diseases more confidently and accurately, fostering greater trust in AI-driven diagnostic tools.

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References

Marwa, E.G., Moustafa, H.E.D., Khalifa, F., Khater, H. and AbdElhalim, E., 2023. An MRI-based deep learning approach for accurate detection of Alzheimer’s disease. Alexandria Engineering Journal, 63, pp.211-221.

Aslam, N., Khan, I.U., Bashamakh, A., Alghool, F.A., Aboulnour, M., Alsuwayan, N.M., Alturaif, R.A.K., Brahimi, S., Aljameel, S.S. and Al Ghamdi, K., 2022. Multiple sclerosis diagnosis using machine learning and deep learning: Challenges and opportunities. Sensors, 22(20), p.7856.

Salem, M., Valverde, S., Cabezas, M., Pareto, D., Oliver, A., Salvi, J., Rovira, À. and Lladó, X., 2019. Multiple sclerosis lesion synthesis in MRI using an encoder-decoder U-NET. IEEE Access, 7, pp.25171-25184.

Soltani, A. and Nasri, S., 2020. Improved algorithm for multiple sclerosis diagnosis in MRI using convolutional neural network. IET Image Processing, 14(17), pp.4507-4512.

Tenghongsakul, K., Kanjanasurat, I., Archevapanich, T., Purahong, B. and Lasakul, A., 2023, May. Deep transfer learning for brain tumor detection based on MRI images. In Journal of Physics: Conference Series (Vol. 2497, No. 1, p. 012015).

Saeedi, S., Rezayi, S., Keshavarz, H. and R. Niakan Kalhori, S., 2023. MRI-based brain tumor detection using convolutional deep learning methods and chosen machine learning techniques. BMC Medical Informatics and Decision Making, 23(1), p.16.

Hossain, S., Chakrabarty, A., Gadekallu, T.R., Alazab, M. and Piran, M.J., 2023. Vision transformers, ensemble model, and transfer learning leveraging explainable AI for brain tumor detection and classification. IEEE Journal of Biomedical and Health Informatics.

Patel, A., Priya, N.G. and Divya, G., 2023, May. Automated Brain Tumor detection using multi-label images of MRI scans and CNNs. In 2023 2nd International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies (ViTECoN) (pp. 1-5). IEEE.

Chaddad, A., Peng, J., Xu, J. and Bouridane, A., 2023. Survey of explainable AI techniques in healthcare. Sensors, 23(2), p.634.

Nazir, S., Dickson, D.M. and Akram, M.U., 2023. Survey of explainable artificial intelligence techniques for biomedical imaging with deep neural networks. Computers in Biology and Medicine, p.106668.

Senturk, Z.K., 2020. Early diagnosis of Parkinson’s disease using machine learning algorithms. Medical hypotheses, 138, p.109603.

Fareed, M.M.S., Zikria, S., Ahmed, G., Mahmood, S., Aslam, M., Jillani, S.F., Moustafa, A. and Asad, M., 2022. ADD-Net: An Effective Deep Learning Model for Early Detection of Alzheimer Disease in MRI Scans. IEEE Access, 10, pp.96930-96951.

Yamanakkanavar, N., Choi, J.Y. and Lee, B., 2020. MRI segmentation and classification of human brain using deep learning for diagnosis of Alzheimer’s disease: a survey. Sensors, 20(11), p.3243.

Karacı, A., 2022. VGGCOV19-NET: automatic detection of COVID-19 cases from X-ray images using modified VGG19 CNN architecture and YOLO algorithm. Neural Computing and Applications, 34(10), pp.8253-8274.

Biju, K.S., Alfa, S.S., Lal, K., Antony, A. and Akhil, M.K., 2017. Alzheimer’s detection based on segmentation of MRI image. Procedia computer science, 115, pp.474-481.

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Published

26.06.2024

How to Cite

P. V. Siva Kumar. (2024). Building Trust in Artificial Intelligence: An Explainable Deep Learning Framework for Brain Disease Detection. International Journal of Intelligent Systems and Applications in Engineering, 12(4), 932 –. Retrieved from https://ijisae.org/index.php/IJISAE/article/view/6315

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Section

Research Article