Automated Primary Brain Tumors Classification of MR Images using Texture Features Extraction and Machine Learning
Keywords:
Brain Tumor, Magnetic Resonance Imaging, Texture Features, Normalization, Classification.Abstract
Among all cancers, brain cancer has the greatest fatality rates due to its difficult detection and misdiagnosis. The ability to distinguish on the basis of variations in texture, shape, intensity, and deep features, makes Magnetic Resonance Imaging (MRI) a popular tool for the diagnosis of brain cancer. These features have been utilized during the classification of brain tumors. This paper proposes a methodology for classifying primary brain tumors in binary class using the texture features of Magnetic Resonance (MR) images. The Gabor 2D filter, Haralick Texture Features (HTF), Edge Continuity Texture Features (ECTF), First-Order Statistical Texture Features (FOSTF), Local Binary Pattern Texture Features (LBPTF), Difference Theoretic Texture Features (DTTF), and Spectral Texture Features (STF) are used for texture feature extraction of brain MR images. The Tanh normalization method further normalized the retrieved features to deal with outliers and dominant features. The Infinite Latent Feature Selection (ILFS) approach is used for feature ranking to find the most pertinent and non-redundant texture features once the features have been normalized. The top 200-ranked features are used for the classification. The proposed method is compared with different supervised classifiers and achieves high classification accuracy with a minimum error rate and better precision, sensitivity, specificity, Mathew Correction Coefficient (MCC), and F1-Score values. An accuracy of 99.4% has been achieved with the cubic Support Vector Machine (SVM) classifier for the Figshare dataset. A comparison has also been made between the proposed method and other state-of-the-art methods.
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K. Dimililer and A. İlhan, “Effect of Image Enhancement on MRI Brain Images with Neural Networks,” Procedia Comput. Sci., vol. 102, pp. 39–44, Jan. 2016, https://doi.org/10.1016/j.procs.2016.09.367.
S. R. Gunasekara, H. N. T. K. Kaldera, and M. B. Dissanayake, “A Systematic Approach for MRI Brain Tumor Localization and Segmentation Using Deep Learning and Active Contouring,” J. Healthc. Eng., vol. 2021, pp. 1–13, Feb. 2021, https://doi.org/10.1155/2021/6695108.
A. Dasgupta, T. Gupta, and R. Jalali, “Indian data on central nervous tumors: A summary of published work,” South Asian J. Cancer, vol. 05, no. 03, pp. 147–153, Jul. 2016, https://doi.org/10.4103/2278-330X.187589.
Q. T. Ostrom, G. Cioffi, H. Gittleman, N. Patil, K. Waite, C. Kruchko, and J. S. Barnholtz-Sloan, “CBTRUS statistical report: Primary brain and other central nervous system tumors diagnosed in the United States in 2012–2016,” Neuro. Oncol., vol. 21, no. Supplement_5, pp. v1–v100, Nov. 2019, https://doi.org/10.1093/neuonc/noz150.
A. Patel, “Benign vs Malignant Tumors,” JAMA Oncology, vol. 6, no. 9. p. 1488, 2020. https://doi.org/10.1001/jamaoncol.2020.2592.
R. Mohan, K. Ganapathy, and A. Rama, “Brain tumor classification of magnetic resonance images using a novel CNN-based medical image analysis and detection network in comparison with AlexNet,” J. Popul. Ther. Clin. Pharmacol., vol. 29, no. 1, pp. e97–e108, 2022, https://doi.org/10.47750/jptcp.2022.898.
G. Latif, D. N. F. A. Iskandar, J. M. Alghazo, and N. Mohammad, “Enhanced MR Image Classification Using Hybrid Statistical and Wavelets Features,” IEEE Access, vol. 7, pp. 9634–9644, 2019, https://doi.org/10.1109/ACCESS.2018.2888488.
M. A. Khan, I. Ashraf, M. Alhaisoni, R. Damaševičius, R. Scherer, A. Rehman, and S. A. C. Bukhari, “Multimodal Brain Tumor Classification Using Deep Learning and Robust Feature Selection: A Machine Learning Application for Radiologists,” Diagnostics, vol. 10, no. 8, p. 565, Aug. 2020, https://doi.org/10.3390/diagnostics10080565.
K. D. Miller, Q. T. Ostrom, C. Kruchko, N. Patil, T. Tihan, G. Cioffi, H. E. Fuchs, K. A. Waite, A. Jemal, R. L. Siegel, and J. S. Barnholtz‐Sloan, “Brain and other central nervous system tumor statistics, 2021,” CA. Cancer J. Clin., vol. 71, no. 5, pp. 381–406, Sep. 2021, https://doi.org/10.3322/caac.21693.
R. Shrwan and A. Gupta, “Classification of Pituitary Tumor and Multiple Sclerosis Brain Lesions through Convolutional Neural Networks,” IOP Conf. Ser. Mater. Sci. Eng., vol. 1049, no. 1, p. 012014, 2021, https://doi.org/10.1088/1757-899x/1049/1/012014.
D. N. George, H. B. Jehlol, and A. S. A. Oleiwi, “Brain tumor detection using shape features and machine learning algorithms,” Int. J. Sci. Eng. Res., vol. 6, no. 12, pp. 454–459, 2015.
K. Herholz, K. Langen, C. Schiepers, and M. James, “NIH Public Access,” vol. 42, no. 6, pp. 356–370, 2014, https://doi.org/10.1053/j.semnuclmed.2012.06.001.Brain.
Y. Abdallah and Y. Mohamed, “History of medical imaging,” Arch. Med. Heal. Sci., vol. 5, no. 2, p. 275, 2017, https://doi.org/10.4103/amhs.amhs_97_17.
H. Kasban, M. A. M. El-Bendary, and D. H. Salama, “A Comparative Study of Medical Imaging Techniques,” Int. J. Inf. Sci. Intell. Syst., vol. 4, no. 2, pp. 37–58, 2015.
J. Seetha and S. S. Raja, “Brain tumor classification using convolutional neural networks,” Biomed. Pharmacol. J., vol. 11, no. 3, pp. 1457–1461, Sep. 2018, https://doi.org/10.13005/bpj/1511.
V. P. B. Grover, J. M. Tognarelli, M. M. E. Crossey, I. J. Cox, S. D. Taylor-Robinson, and M. J. W. McPhail, “Magnetic Resonance Imaging: Principles and Techniques: Lessons for Clinicians,” J. Clin. Exp. Hepatol., vol. 5, no. 3, pp. 246–255, 2015, https://doi.org/10.1016/j.jceh.2015.08.001.
E. I. Papageorgiou, P. P. Spyridonos, D. T. Glotsos, C. D. Stylios, P. Ravazoula, G. N. Nikiforidis, and P. P. Groumpos, “Brain tumor characterization using the soft computing technique of fuzzy cognitive maps,” Appl. Soft Comput. J., vol. 8, no. 1, pp. 820–828, 2008, https://doi.org/10.1016/j.asoc.2007.06.006.
G. Latif, S. B. Kazmi, M. A. Jaffar, and A. M. Mirza, “Classification and Segmentation of Brain Tumor Using Texture Analysis,” in Recent Advances In Artificial Intelligence, Knowledge Engineering And Data Bases, 2010, pp. 147–155.
D. Singh and K. Kaur, “Classification of Abnormalities in Brain MRI Images Using GLCM , PCA and SVM,” Int. J. Eng. Adv. Technol., vol. 1, no. 6, pp. 243–248, 2012.
A. Jayachandran and R. Dhanasekaran, “Brain Tumor Detection and Classification of MR Images Using Texture Features and Fuzzy SVM Classifier,” Res. J. Appl. Sci. Eng. Technol., vol. 6, no. 12, pp. 2264–2269, Jul. 2013, https://doi.org/10.19026/rjaset.6.3857.
W. H. Ibrahim, A. A. A. Osman, and Y. I. Mohamed, “MRI brain image classification using neural networks,” Proc. - 2013 Int. Conf. Comput. Electr. Electron. Eng. ’Research Makes a Differ. ICCEEE 2013, pp. 253–258, 2013, https://doi.org/10.1109/ICCEEE.2013.6633943.
B. Sudha, P. Gopikannan, Shenbagarajan, and C. Balasubramanian, “Classification of brain tumor grades using neural network,” Lect. Notes Eng. Comput. Sci., vol. 1, pp. 567–571, 2014.
Sharma et al., “Brain Tumor Detection based on Machine Learning Algorithms.International Journal of Computer Applications INDIA,” vol. 103, no. 1, pp. 7–11, 2014, [Online]. Available: www.ijcaonline.org
K. Skogen, A. Schulz, J. B. Dormagen, B. Ganeshan, E. Helseth, and A. Server, “Diagnostic performance of texture analysis on MRI in grading cerebral gliomas,” Eur. J. Radiol., vol. 85, no. 4, pp. 824–829, Apr. 2016, https://doi.org/10.1016/j.ejrad.2016.01.013.
J. Sachdeva, V. Kumar, I. Gupta, N. Khandelwal, and C. K. Ahuja, “A package-SFERCB-"Segmentation, feature extraction, reduction and classification analysis by both SVM and ANN for brain tumors",” Appl. Soft Comput. J., vol. 47, pp. 151–167, 2016, https://doi.org/10.1016/j.asoc.2016.05.020.
K. L. C. Hsieh, C. M. Lo, and C. J. Hsiao, “Computer-aided grading of gliomas based on local and global MRI features,” Comput. Methods Programs Biomed., vol. 139, pp. 31–38, 2017, https://doi.org/10.1016/j.cmpb.2016.10.021.
A. Minz and C. Mahobiya, “MR image classification using adaboost for brain tumor type,” Proc. - 7th IEEE Int. Adv. Comput. Conf. IACC 2017, pp. 701–705, 2017, https://doi.org/10.1109/IACC.2017.0146.
A. Ari and D. Hanbay, “Deep learning based brain tumor classification and detection system,” TURKISH J. Electr. Eng. Comput. Sci., vol. 26, no. 5, pp. 2275–2286, Sep. 2018, https://doi.org/10.3906/elk-1801-8.
U. Alqasemi, M. Bamaleibd, and A. Al Baiti, “Classification of Brain MRI Tumor Images,” Int. J. Eng. Res. Technol., vol. 10, no. 03, pp. 119–126, 2021.
A. Elmoufidi, K. EL Fahssi, S. Jai-Andaloussi, N. Madrane, and A. Sekkaki, “Detection of regions of interest’s in mammograms by using local binary pattern, dynamic k-means algorithm and gray level co-occurrence matrix,” in 2014 International Conference on Next Generation Networks and Services (NGNS), May 2014, pp. 118–123. https://doi.org/10.1109/NGNS.2014.6990239.
R. Banan and C. Hartmann, “The new WHO 2016 classification of brain tumors-what neurosurgeons need to know.,” Acta Neurochir. (Wien)., vol. 159, no. 3, pp. 403–418, Mar. 2017, https://doi.org/10.1007/s00701-016-3062-3.
P. S. Shijin Kumar and V. S. Dharun, “A study of MRI segmentation methods in automatic brain tumor detection,” Int. J. Eng. Technol., vol. 8, no. 2, pp. 609–614, 2016.
J. Cheng, W. Huang, S. Cao, R. Yang, W. Yang, Z. Yun, Z. Wang, and Q. Feng, “Enhanced performance of brain tumor classification via tumor region augmentation and partition,” PLoS One, vol. 10, no. 10, p. e0140381, Oct. 2015, https://doi.org/10.1371/journal.pone.0140381.
A. K. Altwairgi, S. Raja, M. Manzoor, S. Aldandan, E. Alsaeed, A. Balbaid, H. Alhussain, Y. Orz, A. Lary, and A. A. Alsharm, “Management and treatment recommendations for World Health Organization Grade III and IV gliomas.,” Int. J. Health Sci. (Qassim)., vol. 11, no. 3, pp. 54–62, 2017, [Online]. Available: http://www.ncbi.nlm.nih.gov/pubmed/28936153%0Ahttp://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC5604271
Choksey et al., “Computed tomography in the diagnosis of malignant brain tumours: do all patients require biopsy?,” J. ofNeurology, Neurosurgery, Psychiatry, vol. 52, pp. 821–825, 1989, https://doi.org/10.1136/jnnp.52.7.821.
P. U. Freda and S. L. Wardlaw, “Diagnosis and Treatment of Pituitary Tumors,” 1999. [Online]. Available: https://academic.oup.com/jcem/article/84/11/3859/2864212
R. A. Buerki, C. M. Horbinski, T. Kruser, P. M. Horowitz, C. D. James, and R. V Lukas, “An overview of meningiomas,” Futur. Oncol., vol. 14, no. 21, pp. 2161–2177, Sep. 2018, https://doi.org/10.2217/fon-2018-0006.
N. Varuna Shree and T. N. R. Kumar, “Identification and classification of brain tumor MRI images with feature extraction using DWT and probabilistic neural network,” Brain Informatics, vol. 5, no. 1, pp. 23–30, Mar. 2018, https://doi.org/10.1007/s40708-017-0075-5.
D. Gabor, “Theory of communication. Part 1: The analysis of information,” J. Inst. Electr. Eng. - Part III Radio Commun. Eng., vol. 93, no. 26, pp. 429–441, Nov. 1946, https://doi.org/10.1049/ji-3-2.1946.0074.
M. R. Ismael and I. A. Qader, “Brain tumor classification via statistical features and back-propagation neural network,” in 2018 IEEE International Conference on Electro/Information Technology (EIT), May 2018, vol. 2018-May, pp. 0252–0257. https://doi.org/10.1109/EIT.2018.8500308.
R. M. Haralick, K. Shanmugam, and I. Dinstein, “Textural features for image classification,” IEEE Trans. Syst. Man. Cybern., vol. SMC-3, no. 6, pp. 610–621, Nov. 1973, https://doi.org/10.1109/TSMC.1973.4309314.
D. Assefa, H. Keller, C. Ménard, N. Laperriere, R. J. Ferrari, and I. Yeung, “Robust texture features for response monitoring of glioblastoma multiforme on T1-weighted and T2-FLAIR MR images: a preliminary investigation in terms of identification and segmentation.,” Med. Phys., vol. 37, no. 4, pp. 1722–36, Apr. 2010, https://doi.org/10.1118/1.3357289.
S. Susan, P. Agrawal, M. Mittal, and S. Bansal, “New shape descriptor in the context of edge continuity,” CAAI Trans. Intell. Technol., vol. 4, no. 2, pp. 101–109, Jun. 2019, https://doi.org/10.1049/trit.2019.0002.
S. R. Telrandhe, A. Pimpalkar, and A. Kendhe, “Detection of brain tumor from MRI images by using segmentation & SVM,” in 2016 World Conference on Futuristic Trends in Research and Innovation for Social Welfare (Startup Conclave), Feb. 2016, no. November 2018, pp. 1–6. https://doi.org/10.1109/STARTUP.2016.7583949.
R. C. Gonzalez and R. E. Woods, “Digital Image Processing,” Pearson Int. Ed., vol. 3, pp. 1–976, 2002.
N. Aggarwal and R. K. Agrawal, “First and Second Order Statistics Features for Classification of Magnetic Resonance Brain Images,” J. Signal Inf. Process., vol. 03, no. 02, pp. 146–153, 2012, https://doi.org/10.4236/jsip.2012.32019.
T. Ojala, “A Comparative Study of Texture Measures With Classification Based on Feature Distributions,” Pattern Recognit., vol. 29, no. l, pp. 51–59, 1996.
S. Susan and M. Hanmandlu, “Difference theoretic feature set for scale‐, illumination‐ and rotation‐invariant texture classification,” IET Image Process., vol. 7, no. 8, pp. 725–732, Nov. 2013, https://doi.org/10.1049/iet-ipr.2012.0527.
C. Feng and Q. Liu, “A study of digital watermark algorithm based on HVS for halftone images,” Adv. Mater. Res., vol. 174, pp. 127–131, 2011, https://doi.org/10.4028/www.scientific.net/AMR.174.127.
D. Kim, Y. Lee, B. Ku, and H. Ko, “Crowd density estimation using multi-class adaboost,” in 2012 IEEE Ninth International Conference on Advanced Video and Signal-Based Surveillance, Sep. 2012, pp. 447–451. https://doi.org/10.1109/AVSS.2012.31.
F. R. Hampel, E. M. Ronchetti, P. J. Rousseeuw, and W. A. Stahel, Robust Statistics. Wiley, 2005. https://doi.org/10.1002/9781118186435.
C. Nwankpa, W. Ijomah, A. Gachagan, and S. Marshall, “Activation Functions: Comparison of trends in Practice and Research for Deep Learning,” pp. 1–20, Nov. 2018, https://doi.org/doi.org/10.48550.
G. Roffo, S. Melzi, U. Castellani, and A. Vinciarelli, “Infinite Latent Feature Selection: A Probabilistic Latent Graph-Based Ranking Approach,” Proc. IEEE Int. Conf. Comput. Vis., vol. 2017-Octob, pp. 1407–1415, 2017, https://doi.org/10.1109/ICCV.2017.156.
F. Melgani and L. Bruzzone, “Classification of hyperspectral remote sensing images with support vector machines,” IEEE Trans. Geosci. Remote Sens., vol. 42, no. 8, pp. 1778–1790, Aug. 2004, https://doi.org/10.1109/TGRS.2004.831865.
D. T. Larose, An Introduction to Data Mining The CRISP-DM. 1999.
L. Rokach and O. Maimon, Data Mining With Decision Trees. 2005.
T. Ramayah, N. H. Ahmad, H. A. Halim, S. Rohaida, M. Zainal, and M. Lo, “Discriminant analysis : An illustrated example,” African J. Bus. Manag., vol. 4, no. 9, pp. 1654–1667, 2010.
D. T. Larose and C. D. Larose, DISCOVERING KNOWLEDGE IN DATA An Introduction to Data Mining Second Edition Wiley Series on Methods and Applications in Data Mining. 2014.
S. J. Delany and P. Cunningham, “An Analysis of Case-Base Editing in a Spam Filtering System,” in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 3155, 2004, pp. 128–141. https://doi.org/10.1007/978-3-540-28631-8_11.
R. Polikar, “Ensemble based systems in decision making,” IEEE Circuits Syst. Mag., vol. 6, no. 3, pp. 21–44, 2006, https://doi.org/10.1109/MCAS.2006.1688199.
C. Cortes and V. Vapnik, “Support-vector networks,” Mach. Learn., vol. 20, no. 3, pp. 273–297, Sep. 1995, https://doi.org/10.1007/BF00994018.
P. Drotar and Z. Smekal, “Comparative Study of Machine Learning Techniques for Supervised Classification of Biomedical Data,” Acta Electrotech. Inform., vol. 14, no. 3, pp. 5–10, 2014, https://doi.org/10.15546/aeei-2014-0021.
N. B. Bahadure, A. K. Ray, and H. P. Thethi, “Image Analysis for MRI Based Brain Tumor Detection and Feature Extraction Using Biologically Inspired BWT and SVM,” Int. J. Biomed. Imaging, vol. 2017, 2017, https://doi.org/10.1155/2017/9749108.
Z. Ullah, M. U. Farooq, S. H. Lee, and D. An, “A hybrid image enhancement based brain MRI images classification technique,” Med. Hypotheses, vol. 143, p. 109922, Oct. 2020, https://doi.org/10.1016/j.mehy.2020.109922.
M. A. Ansari, R. Mehrotra, and R. Agrawal, “Detection and classification of brain tumor in MRI images using wavelet transform and support vector machine,” J. Interdiscip. Math., vol. 23, no. 5, pp. 955–966, 2020, https://doi.org/10.1080/09720502.2020.1723921.
S. Preethi and P. Aishwarya, “Combining wavelet texture features and deep neural network for tumor detection and segmentation over MRI,” J. Intell. Syst., vol. 28, no. 4, pp. 571–588, 2021, https://doi.org/10.1515/jisys-2017-0090.
U. Raghavendra, A. Gudigar, T. N. Rao, V. Rajinikanth, E. J. Ciaccio, C. H. Yeong, S. C. Satapathy, F. Molinari, and U. R. Acharya, “Feature‐versus deep learning‐based approaches for the automated detection of brain tumor with magnetic resonance images: A comparative study,” Int. J. Imaging Syst. Technol., vol. 32, no. 2, pp. 501–516, Mar. 2022, https://doi.org/10.1002/ima.22646.
F. lahmood HAMEED and O. DAKKAK, “Brain Tumor Detection and Classification Using Convolutional Neural Network (CNN),” in 2022 International Congress on Human-Computer Interaction, Optimization and Robotic Applications (HORA), Jun. 2022, no. 2, pp. 1–7. https://doi.org/10.1109/HORA55278.2022.9800032.
M. Gupta, S. K. Sharma, and G. C. Sampada, “Classification of Brain Tumor Images Using CNN,” Comput. Intell. Neurosci., vol. 2023, pp. 1–6, Oct. 2023, https://doi.org/10.1155/2023/2002855.
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