Beyond Speech-to-Text: Voice-to-Voice Generative AI Systems for Emotion-Aware, Real-Time Healthcare Contact Centers

Authors

  • Bhargavi Kalicheti

Keywords:

Voice-To-Voice Generative AI, Speech Emotion Recognition, Healthcare Telephony, Affective Computing, Neural Vocoder, Prosody Modeling, Speech-Native AI, Hipaa Compliance, Real-Time Inference, Multilingual Voice AI

Abstract

Healthcare contact centers represent one of the most demanding environments for conversational artificial intelligence, requiring real-time responsiveness, emotional sensitivity, regulatory compliance, and operational scalability. Traditional speech-based AI systems rely on speech-to-text (STT) and text-to-speech (TTS) pipelines that introduce latency, flatten emotional nuance, and fragment conversational context. Recent advances in generative modeling have enabled a new paradigm: voice-to-voice (V2V) generative AI, where spoken input is transformed directly into spoken output without intermediate text representation. This paper explores the architectural foundations, system design principles, and operational implications of deploying V2V generative AI systems for emotion-aware, real-time healthcare contact centers. We analyze how speech-native representations preserve prosody, cadence, and affect, enabling more human-like interactions across administrative, clinical, and insurance-related telephony workflows. The paper presents a cloud-native reference architecture for V2V systems, examines latency optimization strategies critical for telephony-grade performance, discusses multilingual equity considerations, evaluates safety and compliance requirements in regulated healthcare environments, and outlines evaluation frameworks for emotional fidelity, conversational trust, and operational impact. By moving beyond text-mediated conversational AI, voice-to-voice systems represent a foundational shift toward speech-native intelligence capable of transforming healthcare contact center operations at a national scale.

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Published

17.05.2026

How to Cite

Bhargavi Kalicheti. (2026). Beyond Speech-to-Text: Voice-to-Voice Generative AI Systems for Emotion-Aware, Real-Time Healthcare Contact Centers. International Journal of Intelligent Systems and Applications in Engineering, 14(1s), 894–905. Retrieved from https://ijisae.org/index.php/IJISAE/article/view/8280

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Section

Research Article